MORGAGNI, Giovanni Battista. De Sedibus et causis Morborum.
Venice, Remondini, 1761
2 folio volumes, 395x250 mm. Contemporary hardback binding. Vol. I: Half-title, Frontispiece with engraved Portrait, pages pp. XCVI [including Half-title and Titlepage], 298, [2]. Title page printed in red and black. Author's name followed by the acronym P.P.P.P.
Author’s portrait signed: 'Jean Renard sculp.' [i.e. Giovanni Volpato]. The name of the printer “Giambattista Remondini” appears in the printing license on page XCVI. Vol. II: Pp. 452, including Title-page. The author's name is followed by the acronym P.P.P.
Intaglio vignette on the title pages; text in two columns; woodcut initials, headpieces and endpieces. Handwritten ownership notes dated 1766 on the first endpaper of both volumes. Sign of wear on bindings, internally occasional foxing. Good uncut copy.
First edition, first issue of Morgagni's main work and one of the most important books in the history of medicine.
Garrison & Morton: "one of the most important [works] in the history of medicine." This book contains accounts of an extensive series of autopsies performed by Morgagni, his master Valsalva and other members of his circle. By comparing clinical symptoms with autopsy findings Morgagni laid the foundations of pathological anatomy. The study of diseased organs permanently supplanted the ancient humoral pathology. His work focused attention on the "site" rather than the "nature" of disease, which had been the main concern of medicine since the time of Hippocrates.
The work includes a number of brilliant descriptions of new diseases, some of which have remained classics to this day, particularly those of the heart, blood vessels, lungs, and throat. He described syphilitic (gummata) tumors in the brain, recorded a case of heart block (Stokes Adams disease), identified clinical features of pneumonia with consolidation of the lungs, described lesions in angina pectoris, acute yellow atrophy of the liver, tuberculosis of the kidney, etc.
“A foundation of modern pathological anatomy. Far-reaching, it is one of the critically important works in the history of medicine. In it he (Morgagni) reports precisely and exhaustively the results of almost seven hundred autopsy dissections, introducing and insisting on the concept that the diagnosis, prognosis and treatment of the disease must be based on the exact understanding of the pathological alterations of the anatomical structures" (Heirs of Hippocrates 501). Garrison-Morton: “Morgagni was the true founder of modern pathological anatomy”.
Morgagni's portrait bears the pseudonym “Jean Renard” that Giovanni Volpato used in the first years of his activity as an engraver: the name "Gio. Volpato" also appears at the bottom of the image, on the right.
Copy in first issue: Date on both titles 1761, 1 title in red and black, the second title in black only; 3 'P' and not 4 after Morgagni's name: [P.(ublici), P.(rofessoris), P.(rimari)].
PMM 206; Dibner 125; Norman 1547; Grolier Medicine 46; Heirs of Hippocrates 792; Wellcome IV, 178; Garrison-M. 2276; NLM/Blake 312; Osler 1178; Waller 6672.